International Review of Ophthalmology ›› 2025, Vol. 49 ›› Issue (3): 161-170.doi: 10. 3760/cma.j.cn115500-20250331-25301

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Oculomechanics medicine

He Yuan1, Du Huan1, Ge Ping1, Jia Yuanbo2,3, Xu Feng4, Sun Xinghuai5   

  1. 1Department of Ophthalmology,The Second Affiliated Hospital of Xi'an Medical University, Xi'an 710038, China; 2Department of Hepatobiliary Surgery and Liver Transplantation, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710004, China; 3China Key Laboratory of Surgical Critical Care and Life Support (Xi'an Jiaotong University), Ministry of Education, Xi’an 710049, China; 4MOE Key Laboratory of Biomedical Information Engineering, Bioinspired Engineering and Biomechanics Center, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China; 5Eye & ENT Hospital of Fudan University, Shanghai 200031, China

  • Received:2025-03-31 Online:2025-06-22 Published:2025-06-12
  • Contact: Sun Xinghuai, Email: xhsun@shmu.edu.cn; Xu Feng, Email: fengxu@mail.xjtu.edu.cn
  • Supported by:
    National Natural Science Foundation of China (12225208, 82070964); Outstanding Youth Fund of Shaanxi Province (2022JC-60); International Scientific and Technological Cooperation Projects of Shaanxi Science and Technology Department(2024GH-YBXM-20); Dedicated Funding for the National Key Laboratory for the Prevention and Treatment of Eye Diseases(83000-32030002)

Abstract: With the development of interdisciplinary integration between medicine and engineering, the role of mechanical factors in the pathogenesis, progression, diagnosis, and treatment of ophthalmic diseases has become increasingly prominent, emerging as a focal point in both basic and clinical research.Oculomechanics medicine focuses on the application of mechanical factors in understanding disease mechanisms and developing therapeutic interventions in ophthalmology. Centered on establishing direct correlations between biomechanical parameters of ocular tissues and clinical management, this field organically integrates four key components: ocular biomechanics, ocular mechanobiology, ocular mechanodiagnostics, and ocular mechanotherapeutics. Specifically, ocular biomechanics investigates the mechanical responses arising from biological changes in ocular tissues, while ocular mechanobiology explores biological alterations induced by mechanical forces. Ocular mechanodiagnostics leverages mechanical characteristics to develop novel diagnostic tools for enhanced precision in early disease detection, whereas ocular mechanotherapeutics focuses on formulating personalized treatment strategies through mechanical interventions in ocular tissues.


Key words: Ocular biomechanics, Ocular mechanobiology, Ocular mechanodiagnostics, Ocular mechanotherapy